AIMS: We aimed to assess femoral intima-media thickness(IMT) in a population free of cardiovascular disease. We sought to determine its role on prediction of cardiovascular and cerebrovascular events.  
METHODS: Patients who were scheduled for coronary computed tomographic angiography for evaluation of the coronary arteries in September 2016-June 2017 were included. Carotid and femoral intima- media thickness(IMT) measurements were performed. Coronary artery calcium (CAC) score was recorded. Patients were followed-up for cardiovascular and cerebrovascular events. 
RESULTS: 215 patients(54.85±11.19 years, 47.91% male, median SCORE-TR: 2, median PCE: 6.30) were recruited. At a median follow-up of 24 months, 1 patient suffered from non-fatal stroke and 9 patients underwent coronary revascularization(1 CABG, 8 PCI). 
In subjects with cardiovascular and cerebrovascular events(n= 10), mean distal carotid IMT(cIMT)(p=0.012), mean carotid bifurcation cIMT (p=0.002), mean proximal cIMT(p=0.009), femoral artery IMT(fIMT)(p=0.009) and CAC score(p<0.001) were significantly higher.
Cardiovascular and cerebrovascular events were significantly more common in subjects who had CAC score≥ 300 compared with those who had 0(13.73 vs. 0.69, p<0.001). Subjects who had plaques both at the carotid and femoral arterial beds had significantly higher incidence of events compared to having plaques only in carotid or femoral arterial bed(37.5 vs. 3.57 vs. 0, p=0.003). 
ROC curve analysis showed that fIMT≥0.85 mm predicts the occurrence of cardiovascular and cerebrovascular events with 70% sensitivity and 67.8% specificity(p=0.011). 
CONCLUSIONS: Additional to the carotid atherosclerosis, femoral arterial atherosclerosis, reflected in fIMT and femoral plaques, may add to cardiovascular risk prediction.

02 - FEMORAL INTIMA-MEDIA THICKNESS IS A PREDICTOR OF CARDIOVASCULAR EVENTS IN A LOW-MODERATE CARDIOVASCULAR RISK POPULATION