There is no consensus in the literature about the influence of chronic pain on cognition, then, further studies need to be conducted in order to better investigate this association. Objective: to compare cognitive performance among the groups of elderly caregivers with chronic pain and absence of pain over four years and to identify the associated factors in the improvement/worsening of cognitive decline. Method: Longitudinal study conducted between 2014 and 2018/2019 with elderly caregivers. Interviews were conducted at the participants' homes. Cognition was evaluated by the Addenbrooke's Cognitive Examination (ACE-R), which includes the domains: orientation/attention, memory, verbal fluency, language, spatial visibility skills and total score. Statistical analyzes were performed using the linear mixed model and ANCOVA. All comparisons were adjusted for sex, age, number of medicines and comorbidities, hours of care, depression and stress. Significance level 5%. All ethical precepts have been respected. Results: 104 elderly caregivers divided into two groups: with chronic pain (n=73) and absence of pain (n=31). There was a significant difference over time in cognitive performance in the group with chronic pain in the total score and memory domain of ACER. Despite the intragroup changes, there are no evidences that the group with pain changed more than the group without pain. There are no evidences that the change in pain intensity affects cognition. Conclusion: The elderly caregivers with Chronic Pain had a worse cognitive performance over four years in the total score and memory domain of the ACER but there are no evidences that changed more than No Pain group.

06 - CHRONIC PAIN AND COGNITIVE PERFORMANCE IN OLDER CAREGIVERS: LONGITUDINAL STUDY