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Jun 17, 2019

MASCC/ISOO Annual Meeting on Supportive Care in Cancer

06 - GOALS OF CARE AND ADVANCED CARE PLANNING IN PHASE 1 TRIALS

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goals of care

palliative care

phase 1 clinical trials

advance care planning

Abstract

Abstract

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Keywords

goals of care

palliative care

phase 1 clinical trials

advance care planning

Abstract

Background Cancer patients participating in Phase 1 Clinical trials often have advanced disease, symptoms, and QOL impact from disease and treatment. Analysis used data from a randomized trial in progress testing a palliative care intervention for solid tumor patients on Phase 1 trials to evaluate goals of care and advance care planning. Methods Investigators evaluated patient chart audit data at baseline and 6 months after initiating a Phase 1 trial. Results Mean age of patients (N=284) was 60, 56% were female and 32% were ethnic minorities. Predominant diagnoses were lung cancer (18%), colon (15%) and pancreatic (12%) cancers. Thirty six percent (36%) of these patients died within 6 months of starting the trial. At 6 months post trial initiation, 44% had no advanced care plan and 58% remained full code status. Forty four percent of those who died with full code status. Forty five percent had no documented goals of care conversation and 32% had no proxy decision maker. Thirteen percent (13%) of those who died received chemotherapy in the last two weeks of life. Only 44% of those who died received hospice care and only 57% had received palliative care referrals. Conclusions There are important opportunities to integrate palliative care with cancer clinical trials for best supportive care of these patients. This study concludes in 2019.

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© Copyright 2019 Morressier GmbH.
All rights reserved.