2017 update of Drug interactions detected using Electronic Care Records.
Paul Rafferty, Emma McCarty, Wallace Dinsmore, Claire Donnelly, Carol Emerson, Michael Hunter, Eoin Walker, Say Quah.
Background
In 2014 the pharmacy team completed an interaction screen of all HIV patients on a boosted antiretroviral regimen using recently launched NIECR. We concluded that there was a need for primary and secondary care teams to screen and manage drug-drug interactions (DDI) and for patients to remind practitioners about the important of this. 56 patients in 2014 needed urgent clinical intervention.
Method 
In 2014 we reviewed all patients on a boosted ARV regimen for DDI, we continued this work with all patients, and this year we reviewed our interaction screening database, to assess the following 
1.	Documentation of an interaction screen 
2.	How many patients were issued medication by their GP
3.	Of these, what percentage interacted?
4.	Are serious Drug-drug interactions (DDI) still an issue?  
Results
1093 unique patient records, 887 (81.2%) have a recorded H&C number and interaction screen. 
468/887 patients (52.8%) are prescribed medication by their GP with no or no significant interactions.
235/887 patients (26.5%) are prescribed medication by their GP where an interaction is identified by the MDT and managed accordingly either by the clinic or in conjunction with the GP and patient.
118/887 patients (13.3%) do not obtain any medication from their GP.
30/887 patients (3.4%) had documentation which was incomplete
15/887 (1.7%) were not on any ARV’s
9/887 patients (1%) have opted out of NIECR 
8/887 patients (0.9%) key demographics did not match which prevents NIECR verification.
0.5% (4) patients required an immediate clinical intervention compared to 17.6% (56) patients in the 2014 report.
Conclusion
The number of patients prescribed medications by their GP has increased from 45% in our 2014 report to 79.3% in this review.
There has been a reduction in the number of interactions detected and the number of patients requiring an immediate clinical intervention.
A medicines reconciliation and interaction screen before initiating/switching treatment at review and a pharmacist screen prior to a clinic review has enabled us to avoid clinically significant DDI.

2017 update of drug interactions detected using Electronic Care Records (ECR)

The Joint Annual Conference of the British Association for Sexual Health and HIV & the Society for the Study of Sexually Transmitted Diseases in Ireland