Objective: To compare the prevalence and cause of hypoglycemic attacks in diabetic patients visiting emergency room both year 2010 and 2015.
Methods:  Diabetic patients with severe hypoglycemia in 2010 and 2015 were evaluated at emergency visit. 
Results: Among the cases, 33 and 22 patients were detected severe hypoglycemia in 2010 and 2015. Most of severe hypoglycemic patients were attributed to either sulfonylurea(SU) or insulin in both observed years. Patients attributed to using SU significantly　decreased from 77% to 36%. In contrast, patients attributed to insulin increased from 36% to 64%. Conclusion: As DPP4 inhibitors has been widely used in Japan, severe hypoglycemic cases related to SU administration seems to have decreased　in number.

Comparative studies on incidences and causes of hypoglycemia with diabetes observed at emergency room from 2010 to 2015