COMPARISON OF EPIDEMIOLOGICAL, CLINICAL, LABORATORY AND RADIOLOGICAL FEATURES OF 229 HOSPITALIZED DIABETIC AND NON-DIABETIC PATIENTS WITH PULMONARY TUBERCULOSIS IN PULMONARY DEPARTMENT AT KHMER-SOVIET FRIENDSHIP HOSPITAL, CAMBODIA

THENG Heak1, VANN Mich1,2, SUM Satha1,3
(1)	University of Health Science
(2)	Khmer-Soviet Friendship hospital
(3)	Calmette hospital

Background: Diabetes mellitus (DM) is a known risk factor for tuberculosis (TB). The patients with DM had a threefold to fourfold increased risk of developing TB. The prevalence of TB is higher in developping countries compared to developped countries. And with the increasing prevalence of type 2 diabetes in developping countries like Cambodia, many diabetic patients will have a great risk of having TB. 

Objectives: The aim of this study is to investigate the impact of DM on the epidemiological, clinical, biological and radiological features of pulmonary TB.

Patients and Methods: In this retrospective study, the informations of 229 admitted pulmonary TB patients with BK (+) in the pneumology department of Khmer-Soviet Friendship hospital in Phnom Penh from 1st January 2013 to 30th June 2016 was extracted from their medical files. The patients were divided into two groups as TB with DM (n =62) and TB without DM (n =167). The related data on epidemiology, signs, symptoms, biological tests, radiology and sputum smear or bronchoaveolar fluid examination in both groups were compared in STATA by using chi squared test and t-test.

Results: The mean age of TB with DM is higher than TB only (57.4 ± 13.1 vs. 48.1 ± 19.3). The Epidemiological, clinical, biological features, sputum smear and radiological findings are not significantly different in TB + DM and TB only.  And it is noted in our study most of diabetic patients have an elevated fasting plasma glucose.

Conclusions: The result of our study shows that there is no difference in term of epidemiological, clinical and radiological features of pulmonary tuberculosis in both diabetic and non-diabetic patients in Cambodia.

Keywords: Pulmonary tuberculosis with BK (+); Diabetes Mellitus

The comparison of epidemiological, clinical, biological and radiological features of pulmonary TB among TB+DM vs TB-only