Introduction: Recently it has been postulated that the objective of mechanical thrombectomy should be to reach the value 2C/3 on the new modified TICI scale. Our aim is to test if indeed there are differences in  functional prognosis between TICI-2B and TICI2C/3 patients in our series of thrombectomies with recanalization greater than mTICI-2A (recanalization > 50%).
Material and Methods: Retrospective observational study in a prospective, consecutive and single-center cohort of patients with ischemic stroke secondary to arterial occlusion of the anterior circulation; subjected to endovascular treatment and recanalization greater than 50%. The association between good functional prognosis (mRs2) at three months and the arteriographic pattern of recanalization was established. Additionally, other clinical variables considered potential predictors of functional result (age, sex, NIHSS, number of attempts, past history of vascular risk factors, time to start of procedure) were analyzed and included in the multivariate analysis.
Results: 134 patients were recruited, 52% male, mean age: 69.53 (35-90), initial NIHSS (median): 17 (3-27). The following clinical variables were found to be associated with functional prognosis: age, grade of recanalization, previous history of arterial hypertension and ischemic cardiopathy. Patients classified as TICI-2C/3 showed the best functional prognosis (odds ratio 2.011; 95% confidence interval 1.346-3.004, p=0.005) compared to those classified as TICI-2B. In logistic regression TICI-2C/3 recanalization (p=0.017) was an independent predictor of good functional outcome.
Conclusions: Functional outcome is substantially better in those patients classified as TICI-2C/3. This pattern of recanalization should be the final objective of endovascular treatment.

DOES TICI 2C/3 MECHANICAL RECANALIZATION INFLUENCE FUNCTIONAL PROGNOSIS IN STROKE COMPARED TO TICI 2B?