Among different types of diabetes complications, renal manifestations are one of the most common complications in diabetic patients. This study tries to identify the key risk factors for those patients who are more likely to be diagnosed with diabetes type 2 with renal manifestations. The study used the NIS Core datasets from year 2007 to 2012 obtained from the HCUP Central Distributor. Out of total 148,283 records, patients who were diagnosed with Diabetes type2 with renal manifestation with age of 18 years and older were selected. Logistic regression model assisted to identify that which independent variable is significant in predicting the dependent variable Diabetes Type II with Renal Manifestations. In this study, age and race were found to be the strongest risk factor for diabetes-related renal complications. The study provides evidence of a universally true relationship between Vitamin D deficiency and diabetes-associated renal complications. Furthermore, hyperlipidemia, hypercholesterolemia and obesity were found to be statistically significant risk factors for renal complications. Finally, age, gender, smoking, alcohol abuse, hypertension, and hyperglyceridemia were also found to be statistically significant risk factors for renal complications, but this relation was weaker than in previously identified cases. Family history of diabetes and asthma were found to be statistically insignificant in the model.