Background: The conduction of randomized clinical trials (RCTs) in Brazil with post-stroke individuals presents challenges in recruitment, adherence and retention process. Understanding these challenges can assist researchers in conducting future RCTs. Purpose: To investigate the feasibility of conducting a RCT (ClinicalTrials.gov NCT02937480) in the city of Belo Horizonte/Brazil with post-stroke subjects in the chronic phase of stroke. Methods: Ethical commitment from Brazil approved the present study. Eligible participants were randomized to the experimental (task-specific training program) or control (stretching, memory exercises and health orientations) group. Thirty-six intervention sessions of 60-minutes, three times/week, were offered. Results: A total of 952 individuals were identified, but only 67 (7%) accepted to participate and were evaluated. Twenty-two (33%) subjects were excluded, mainly because they did not meet the eligibility criteria (n=12;55%). Forty-five (67%) participated of the interventions. Of these, 12 (27%) abandoned the study, mainly due to lack of interest (n=5;42%) or the appearance of another health problem/indisposition not related to interventions (n=4;33%). At the end, 33 subjects (73%) were retained in the study and had an adherence rate of 81%. The main reasons for absence from the sessions were medical visits (n=61;29%) and indisposition (n=46;22%). Conclusion: The number of individuals who accepted to participate in the study was low. There was a good rate of adherence to the protocol, however, the dropout rate was high. Therefore, other barriers such as lack of interest in proposed activities and the appearance of other health problems should be considered when planning a RCT for this population.

FEASIBILITY OF A RANDOMIZED CONTROLLED TRIAL CONDUCTED IN BELO HORIZONTE/BRAZIL WITH POST-STROKE INDIVIDUALS