Objectives: The goal of the study was to compare the clinical impact of different methods of glycemic control and intensive insulin protocol. Maintenance of controlled blood glucose levels results in fewer complications (eg. Bacteremia) and reduces mortality in critically ill patients.The accuracy of blood glucose measurement and adopted insulin protocol results in reaching target blood glucose level.

Methods: The analysis of blood glucose levels measured from capillary blood and/or venous blood according to the tabular method protocol (SPIRINT-Specialised Relative Insulin and Nutrition Table) and computerized intensive insulin dosing (Gluco Stabilizer Program). Any other factors affecting the instability of glucose level [like: healing manipulations, dressings/bandages, surgical procedures] were not analyzed.

Results: Levels of glucose in the venous blood and capillary blood for ICU patients, were compared. On the basis of glucose levels the dose of insulin was calculated - based on the tabular method [SPIRINT Specialised Relative Insulin and Nutrition Table] and using computer analysis method [Gluco Stabilizer Program, computerized intensive insulin dosing]. Cases of hyperglycemia and hypoglycemia where analyzed as well.

Conclusion: There is no optimal method for assessing blood glucose levels for patients with severe burns.

In the tabular method [SPIRINT Specialised Relative Insulin and Nutrition Table] the insulin therapy is interrupted as a result of achieving the expected level of glucose. In the computer method [Gluco Stabilizer Program] the insulin therapy is maintained for several hours despite achieving the desired level of glucose. The computer method results may be disturbed by the computer malfunction/computer comptation failure.

Insulin therapy in severe Burns - methods of glicemic control and intensive insulin protocol.