Background:
Role of maternal vitamin D status during pregnancy has been acknowledged to be associated with various neonatal outcomes such as prematurity, small gestational age (SGA) and infant respiratory health. Evidence regarding infant atopic allergy is however inconsistent and the role of vitamin D should be explored. 

Objective: 
This systematic review attempts to review studies on the association between maternal vitamin D status during pregnancy and the outcomes of atopic eczema, wheezing and respiratory tract infections (RTIs) in the first year of life.

Methods: 
Literature search from PubMed, MEDLINE, ProQuest, Scopus, CINAHL, the Cochrane Library and Academic Search Premier was performed. Study selection: The literature published up to September 2017 was searched for studies reporting on the association between maternal vitamin D during pregnancy, wheezing, eczema and respiratory infections in the first year of life. Data extraction: About 6765 articles were identified and 32 studies met the inclusion criteria. Of 32 studies, 6 studies were identified after full review. 

Results: 
One study showed that higher maternal vitamin D concentration during pregnancy increases risk of eczema in the first year of life while 2 studies reported lower risk of RTIs in the first year of life. No association were found in wheezing outcomes. 

Conclusion: 
This systematic review found insufficient evidence of the protective role of vitamin D concentration during pregnancy in minimizing the risk of allergy (eczema, wheezing) and RTIs in infants.

MATERNAL VITAMIN D STATUS DURING PREGNANCY AND THE RISK OF ECZEMA, WHEEZING AND RESPIRATORY INFECTIONS IN THE FIRST YEAR OF LIFE: A SYSTEMATIC REVIEW