Background. Fatigue and musculoskeletal pain are two of the main symptoms in patients with chronic fatigue syndrome. There is lack of knowledge how pain interacts with fatigue as well as with other bodily symptoms. The aim of this study was to investigate a relationship between different bodily symptoms as well as outcomes of self-scored questionnaires in relation to pain intensity during the last week.
Method. 318 patients (80% women, median age 45 years old) fulfilled questionnaires regarding their body symptoms, emotional status, fatigue and quality of life. Health-related (SF-36, EQ5D), emotional (HADS) and fatigue-related questionnaires (MFI) as well as self-scored symptom questionnaire were analysed together with patient reported data on symptom duration and time spent in lying position in the bed. Results were analysed by linear regression model. 
Results. Pain intensity during the last week was approximately 5 according to 10-point Numeric Rating Scale. It was predicted by general pain and joint pain according to symptom questionnaire, as well as by bodily pain in SF-36, anxiety in HADS and health quality scale in EQ5D. Fatigue measured by MFI-20 and by symptom questionnaire did not predict pain intensity, neither depression in HADS and SF-36 dimensions, except “bodily pain”. Self-reported duration of symptoms and time spent in the lying position in bed did not predict pain intensity.
Conclusion. Pain seems to be an independent factor and not related to fatigue or other symptoms in patients seeking for chronic fatigue syndrome .

IS PAIN MEDIATED INDEPENDENTLY AMONG OTHER SYMPTOMS IN PATIENTS SEEKING FOR FATIGUE?