and 1 other(s)
Introduction The efficacy of decontamination is one factor attributed to the level of infection risk associated with needle-free connectors. However, the optimal decontamination method for such devices is still unresolved. The objective of this study was to determine if a continuous passive disinfection cap is as effective as standard cleaning for the microbial decontamination of injection ports of two types of needle-free connectors. Method The injection ports of needle-free connectors were inoculated with Staphylococcus aureus and allowed to dry. Disinfection caps containing 70% (v/v) isopropyl alcohol (IPA) were attached to the connectors for one, three or seven days and were compared with needle-free connectors cleaned with wipes containing 2% (w/v) chlorhexidine gluconate (CHG) in 70% (v/v) IPA. The number of S. aureus remaining on the needle-free connectors was determined. Median log10 reductions and 95% confidence interval (CI) were calculated and data analysed using the Mann-Whitney test. Results The application of the disinfection cap resulted in a significantly higher reduction in the number of surviving S.aureus than the wipe containing 2% (w/v) CHG in 70% (v/v) IPA. Indeed, a >5 Log10 reduction in CFU was achieved at each time point. Discussion & Conclusion The disinfection caps resulted in a significantly higher reduction in S.aureus on the injection ports when compared to the use of a wipe containing 2% (w/v) CHG in 70% (v/v) IPA. These results corroborate the lower rates of central-line associated bloodstream infection (CLABSI) demonstrated with the use of disinfection caps in clinical studies.
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