Objectives: Target concentration infusion (TCI) is a computerized infusion system which set target site propofol concentration at demanded time point. Unmatched syringe brands and syringe mode could lead to significant drug dosage error. We want to verify the importance of mode selection and calibration for TCI use
Methods: Two different 50ml syringes were tested for Fresnius orchestra base workstation and orchestra model. We used a fixed-volume mode, and a fixed-duration mode to verify the error for fluid delivery. Average measurement errors in percentage and in total volume were recorded.
Results: Unmatched syringe modes could lead to systemic error from 5% to 18% in both syringes. In 2 hours infusion, the infusion volume could vary from 6ml to 17ml. 
Conclusions:  Self-correction to identify the compatibility of the syringe and infusion pump before use should be incorporated into standard practice. Unmatched syringe and syringe mode could be an error for drug delivery.

Unmatched syringe pumps and syringes lead to significant pump flow error