Often it all begins with a significant technical problem that needs to be solved: How can shrinkage stress that develops during polymerization be minimized? During this collaborative effort, many addition fragmentation monomer (AFM) macromolecules were designed and synthesized. Ultimately, the team collectively identified a preferred AFM that addressed the key articulated needs! After the selection and successful bench-scale synthesis of the preferred AFM, the team embarked on a methodical journey to scale up the monomer for the product development and commercialization phases of the program. This presentation will highlight the extensive technical efforts associated with the development and optimization of a practical, robust, multi-step, synthetic scaleup process of this novel AFM.

Addition-fragmentation-monomers: Size does matter!

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.