Trocheliophorolide A is a natural product isolated from soft coral found in the Gulf of Aqaba in the Red Sea. This compound is of interest due to its antimicrobial effects and the structure of its unsaturated side chain. Our convergent route focuses on constructing the novel unsaturated side chain and coupling it via a Suzuki cross-coupling to a vinyl borane moiety. This presentation will address progress made toward the formation of the chiral vinyl borane and the challenges faced with the various hydroboration protocols.<br/>

Efforts toward the total synthesis of trocheliophorolide A:  Assessing a cadre of hydroboration techniques to afford a viable coupling partner

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.