In prediabetic and hyperglycemic conditions, increased flux of glucose enters the polyol pathway. Aldose Reductase, a member of the Aldo-Keto reductase protein family, catalyzes glucose reduction. Furthermore, Aldose Reductase is inhibited by Isopropyl 2-(4-(4-chloro benzoyl)phenoxy)-2-methylpropanoate, which is known as Fenofibrate. Clinical administration of Fenofibrate has been substantiated to aid in treating hyperlipidemia, heart disease and diabetic complications. Earlier fibrates were believed to act agonistically with the nuclear receptor: peroxisome proliferator-activated receptor α (PPARα). Herein, we present the properties of reduced Fenofibrate, Fibratol.

Derivative of isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate: Fibratol

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.