Electrochemistry has made major contributions to organic synthesis through its “green” methodology, higher atom economy, and minimal waste. Organic electrosynthesis utilizes electrical current to drive the activation of organic molecules via the removal or addition of electrons. Due to its selective redox of organic molecules, organic electrosynthesis can perform reaction transformations that have not been generated traditionally through the use of conventional chemical reagents. Electrochemistry is a beneficial asset for chemists providing clean transformations, mild reaction conditions, simple scalability, high functional group tolerance, low energy consumption, and a step away from the use of toxic redox reagents. Through this research, we have developed a strategic electrochemical approach to perform this Csp<sup>3</sup>–H bond functionalization on C-H bonds adjacent to oxygen and nitrogen, using an undivided electrolytic cell with graphite electrodes as both anode and cathode. The identification of the optimal conditions are currently under investigation in the laboratory.

Functionalization of Csp<sup>3</sup>-H bonds via copper catalyzed electro-organic chemistry

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ACS Spring 2020 National Meeting & Expo

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Functionalization of Csp3-H bonds via copper catalyzed electro-organic chemistry

Functionalization of Csp³-H bonds via copper catalyzed electro-organic chemistry