Regulatory changes in Europe in 2014 allowed GC-MS/MS to be used for confirmatory analysis and control of maximum levels (MLs) and action levels (ALs) of dioxins and dioxin-like compounds in food and feed samples. In this study, the performance of a GC-MS/MS system equipped with an Advanced Electron Ionization (AEI) source was evaluated for the routine analysis of dioxins, dioxin-like PCBs and marker PCBs in solvent standards and food/feedstuff samples. Sample extracts were analysed on identical Thermo ScientificTM TSQTM 9000 GC-MS/MS systems. Chromatographic separation was performed using a TG-Dioxin capillary GC column. Acquisition, processing, and reporting of the data were performed using Thermo Scientific™ Chromeleon™ 7.2 Chromatography Data System (CDS) software. Excellent agreement between the measured TEQ values and the supplied reference values from the EU-RL was obtained. A custom LOQ standard was also analysed at regular intervals throughout all PCDD/F sequences, in order to demonstrate the sensitivity required to maintain LOQs compliant with 1/5th maximum levels. Ion ratio tolerances were maintained at ±15% and RF deviation of less than 30% from the calibration average. System stability was tested by analysing dioxin samples for approximately two weeks.

EU compliant routine quantitative dioxin, dioxin-like compounds by GC-MS/MS with advanced electron ionisation source

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.