Antibiotic resistance is an expanding problem, and is propelling the idea of inhibiting bacterial virulence into modern research literature. One mechanism of bacterial virulence that is being explored as a potential target for treating bacterial infections is the type III secretion system (T3SS), which is used among some Gram-negative pathogens. We have developed a method for screening inhibitors of the T3SS. Here I will review the method I have developed as well as a selection of the compounds I have screened.

Method development for the screening of type III secretion system inhibitors

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.