Super-resolution imaging is used to explore the effect of temperature on thiolated DNA bound to gold nanostructures. For these studies mixed monolayers of thiolated DNA and short alkane thiols were self-assembled on nanosphere lithographically produced gold nanoparticle arrays. The effects of thermal pre-treatments on the nature of transient binding interactions between surface tethered and solution phase strands of DNA is explored using DNA-PAINT. These studies reveal how elevated temperatures affect thiolated DNA bound to gold.

Temperature dependent investigation of thiolated DNA on gold nanoparticle arrays

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.