The research presented involves the design, synthesis, and biological analysis of GPR55 antagonists. The molecular scaffold is based upon a structure that has been found to selectively antagonize GPR55. Utilizing an elegantly simple and novel synthetic route to diversify the original molecule at multiple positions has allowed for preparation of various analogs and the successful synthesis of gram quantities of one of the compounds.

Rational design, synthesis, and biological analysis of GPR55 antagonists

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.