Dibenzo-fused 7-membered heterocyclic ketones have been shown to possess central nervous system (CNS) pharmacological activity. Current methods for synthesizing these compounds involve highly acidic or extreme reaction conditions. These reaction conditions prohibit the integration of particular functional groups. The goal of this work is to develop a new method of preparing these compounds which would enable the preparation of these compounds under milder conditions and permit acid-labile functional group substitutions on the aromatic rings.

Novel preparation of dibenzo-fused seven-membered ring heterocyclic ketones

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.