A new cavitand structural motif has been developed by modifying tri-quinoxaline resorcinarenes.  The unsymmetrical resorcinarene cavitands were synthesized by several steps. Diversity at one of the arm positions to make different cavitand walls is a highlight of the work.  Our group has researched the area of functionalization of the upper part of resorcinarenes.  We have synthesized chiral resorcinarene-based deep cavitands for the sequestration of guests of large sizes. In this report we give our success in synthesizing different quinoxalines to modify the upper rim of the resorcinarene host.  H-NMR, IR and ESI-TOF mass spectrometry afforded the characterization of the unsymmetrical resorcinarene cavitands. Functionalization of the tri-arm resorcinarene with newly designed chiral and achiral arms is the main goal of our research. The following figures are represented the whole main of work. 

Synthesis and functionalization of cavitands with a new arm for chiral recognition

243rd National Meeting (2012)

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