In an era of dramatic change in the pharmaceutical industry the pressure on discovery synthetic chemistry to deliver target compounds in the shortest possible time and using reduced resources is greater than ever. This is set alongside a greater understanding of medicinally relevant chemical space and a desire to access novel areas within this space.  As a consequence of these factors synthetic chemists are being asked to synthesize more complex target structures in a more efficient manner.Only by changing the way we work presently, seeking to fully embrace new methodologies and develop new ones of our own will we be able to successfully access these complex target structures. The focus of this talk will be to highlight what the synthetic chemistry community in AstraZeneca has done to tackle these issues.

Changing synthetic requirements in medicinal chemistry

243rd National Meeting (2012)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.