The Custom Designed Media department within GE has developed new BioProcess affinity resins for the purification of e.g. Kappa and Lambda Fab's but also for well-established r/n plasma proteins such as Factor VII, Factor VIII, Alpha-1 Antitrypsin and even affinity purification of Adeno associated viruses all in close collaboration with specific customers allowing for purities >95% in one step and in high recoveries. The development work behind these resins will be described in more detail as well as some of the other potentials that these resins also offer. Considering that this is the first generation of affinity resins time will also be spent on discussions on how the next generation of these resins may be improved to meet future needs from the industry.

Novel affinity platforms for the purification of r/n proteins and antibody fragments

243rd National Meeting (2012)

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