We studied the role of 3,4,9,10-perylenetetracarboxylic diimide microfibers (PDIMF) used to develop a highly sensitive aptasensor with 1,1'-oxalyldiimidazole chemiluminescence  (ODI CL) detection. PDIMF was prepared with (1) 30-minute sonication of PDIM dissolved in THF and (2) 2-time washing of products by centrifugation with water. Texas Red-labeled aptamer (TRA), capable of binding with ochartoxin A (OTA), emitted strong ODI CL in the absence of PDIMF. However, CL emission of TRA was quenched in the presence of PDIMF. The ratio (CL0/CL) of TRA CL emission depends on the concentration of PDIMF because PDIMF adsorbs TRA. However, CL emission of TRA quenched by ODIMF was enhanced in the presence of OTA. This result indicates that the role of PDIMF in developing an aptasensor is similar to that of carbon nanotube. Thus, we investigated the similarity and differences between PDIMF and multi-walled carbon nanotube applied to developed highly sensitive aptasensors with ODI CL detection.

Role of 3,4,9,10-perylenetetracarboxylic diimide microfibers in developing an aptasensor with 1,1'-oxalyldiimidazole chemiluminescence detection

244th National Meeting (2012)

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