The development of atomic force microscopy, magnetic tweezers, and optical tweezers has greatly enhanced our ability to manipulate matter at the nanoscale. However, these technologies have significant limitations, for example the challenge of manipulating multiple objects in parallel or simultaneously tracking and manipulating objects with nanometer scale precision. Here, we describe a technology platform termed M3 technology, which combines magnetic quantum dots, micropatterned magnetic field engineering, and molecular motor-based control, to overcome these limitations. Some of its key capabilities will be presented here, including: (1) manipulation and tracking of multiple individual nanoparticles and cells (leucocytes), (2) multiplexed sub-femtomolar detection and isolation of protein and/or DNA molecules, and (3) steering, capture, and shape manipulation of self-assembled structures already in motion. This highly versatile technology platform will lead to numerous new opportunities in nanotechnology, chemistry, and bioengineering.

Magnetic quantum dot enabled technologies for nanoscale manipulation

245th National Meeting (2013)

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