Brain tissue requires among the highest levels of metals in the body for cognition and sensory and motor function, including transition metals like copper and iron, but at the same time mismanagement of labile metal pools is a hallmark of aging and neurodegeneration. Our laboratory works at the interface of chemistry and neuroscience by creating and applying new chemical tools to study metals and small-molecule signal/stress agents in brain systems by molecular imaging. The design, synthesis, and evaluation of our most recent platforms and their use in live cell, tissue, and animal settings will be presented.

Award Address  (Nobel Laureate Signature Award for Graduate Education in Chemistry Avantor™ Performance Materials). Metals in the brain: Probing their chemistry by molecular imaging

245th National Meeting (2013)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.