There has been significant interest in photoluminescent Silicon (Si) nanoparticles for biological applications because they are considered to be both biocompatible and biodegradable. This lab has developed the synthesis of Mn2+ and Fe3+ doped Si nanoparticles for combined fluorescent and magnetic properties. By combining magnetic resonance imaging (MRI) with optical imaging or positron emission tomography (PET), clinical applications become a possibility. The addition of paramagnetic ions to silicon nanoparticles allows for optical detection with magnetic resonance imaging techniques. A radioisotope can be added to the shell of these nanoparticles providing additional detection via PET. The synthesis of metal doped Si nanoparticles with zirconia-silica shells will be presented. The resulting nanoparticles were characterized by TEM, ICP-MS, UV-vis, FT-IR, relaxivity, EPR, and fluorescence spectroscopies. The synthesis and characterization will be presented and the nanoparticle properties will be compared.

Synthesis and characterization of metal doped Silicon nanoparticles

246th National Meeting (2013)

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