Fluorescent materials are used in various fields to investigate a biological mechanism of a cell. The fluorescence labeling, as one of the analytical techniques, is commonly used to probe the structure of living cells. The fluorescence materials currently used in these fields are generally either organic molecules or inorganic semiconductors. Organic materials possess a serious drawback of the fluorescence quenching and inorganic materials have critical cyto-toxicity problem when used in a bio cell. Thus, many need new fluorescent material to overcome these problems. We developed a new fluorescent material to overcome these problems by introducing a heterocyclic structure of excited-state intramolecular proton transfer since the molecular structure showed remarkable photophysical property and anticipate it is applied in the fluorescence labeling. Quinoline/THF solution is injected to the diacetylene vesicles of diameter of few 100 nm. As expected, synthesized quinoline nano assembly has the fascinating optical property.

Enhanced fluorescence of nano-colloid and its application on a targeted immunofluorescence labeling

247th National Meeting (2014)

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