Invasive pneumococcal disease (IPD) is one of the leading causes of illness in adults and children worldwide. IPD is caused by the common gram positive bacterium Streptococcus pneumoniae, of which over 90 different serotypes are known to exist. In this symposium we will report on the lessons we have learned from our total synthesis of the repeating pentasaccharide unit of pneumococcal serotype 31 (PS31), a highly invasive strain of Streptococcus pneumoniae responsible for rising mortality rates in adult patients in Europe.

Lessons learned from the total synthesis of the repeating pentasaccharide unit of pneumococcal serotype 31

247th National Meeting (2014)

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