Excellent SERS platform has the ability for ultra-sensitive chemical and biological  toxin sensing and providing its fingerprint. Here we will discuss our recent report on the development of chemically stable highly efficient SERS platform using functionalized graphene oxide-plasmonic gold nanoparticle hybrid. Experimental data with melamine and bacteria show that the SERS enhancement factor for hybrid platform is about two orders of magnitude higher than only nanoparticle. Our results demonstrate that in hybrid SERS platform, graphene oxide will enhance the SERS signal via chemical enhancement and the nano-popcorn will enhance the SERS signal via electromagnetic enhancement. We show that hybrid SERS platform can be used for highly selective and ultra-sensitive detection of melamine in parts per quadrillion level from food sample. Our reported results provide a good approach for developing ultra-sensitive SERS platform for toxin chemical detection and analysis from food.

Label-free SERS detection of chemical and biological toxin from food sample using hybrid graphene oxide

247th National Meeting (2014)

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