The exploitation of efficient and environment-friendly antimicrobials is urgent at present, because of many fungi resistance to synthetic fungicides and high-level toxic residues in the products. The plant essential oil and extracts have long been recognized to be a potential source of antimicrobial agents. The procedure invloves the separation of lead compounds from natural products and the modification of structure and synthesis of derivatives. In this study, ionone, �-ionone, methyl ionone, iso-methyl ionone, irone and lemonile were synthetized from natural citral. The antifungal activities of six citral derivatives on four species plant pathogens were studied. Results showed that these derivatives have an excellent inhibitory effect against Sclerotinia sclerotiorum, Rhizocitonia solani, Gloeosporium piperatum and Phytophthora capsici. With increasing concentration, the antifungal activities are enhanced. Among them, IC50 (50% of inhibitory concentrations) of ionone against Sclerotinia sclerotiorum, Rhizocitonia solani, Gloeosporium piperatum, and Phytophthora capsici was 37.22 �g/ml, 14.02 �g/ml, 50.23 �g/ml and 39.03�g/ml, and IC50 of �-ionone against Sclerotinia sclerotiorum, Rhizocitonia solani, Gloeosporium piperatum and Phytophthora capsiciwas 9.87 �g/ml, 26.25 �g/ml, 15.77 �g/ml and 22.43 �g/ml, respectively. It implies that citral derivatives have strong fungicidal activities and could be used as an alternative to synthetic fungicides for controlling certain important plant fungal diseases.

Antifungal activity of citral derivatives on plant pathogen

247th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.