Surface Plasmon Resonance (SPR) has been used few decades for label-free detection and characterization of biochemical kinetics and affinities for many different types of analysts. The physical phenomena is not limited to biochemistry, but is applicable to many other nanoscale characterization.[1] Aside of the traditional interactions, Multiparametric Surface Plasmon Resonance (MP-SPR) can be utilized to determine unique refractive index (RI) and thickness (d) of ultrathin films (d 0.5-100 nm) without knowledge of the RI of the material. These are important properties for many thin film coating industries and applications, and important knowledge in biomaterials also. The new method allows measurement of these properties for both dielectric layers, but also for metals and metal-like coatings that are difficult to measure with other optical methods. Two new methods utilizing MP-SPR have recently been introduced, either measuring in two different media (2M) with high RI difference, such as air and water [1-3], or at two or more different wavelengths (2W) of light [2,3] in order to characterize properties of ultrathin films. Strongly light absorbing materials, such as metals and semiconductors, have been difficult to measure with traditional thin film measuring optical methods, such as ellipsometry because they are mostly non-transparent materials [4]. For plasmon generation needed for MP-SPR this is not as crucial issue and even multilayered nanolaminates can be characterized. With the ability to characterize both kinetics and nanoscale layer properties, MP-SPR is an effective tool for nanomaterial, biomaterial and biochemical interactions research. This makes the MP-SPR a powerful tool for multidisciplinary research, where both material physical- and interaction properties are characterized.  [1] Albers, Vikholm-Lundin, Nano-Bio-Sensing, 1st, Springer 2010[2] Liang, et al., Sens.Act.B,149 (1), 2010, 212-220[3] Granqvist et al. Langmuir 29  (27), 2013, 8561-8571[4] Hilfiker et al., Thin.Sol.Films, 516 , 2008, 7979-7989[5] Sadowski et al. Opt.Eng., 34  (9), 1995, 2581-2586

MP-SPR: New optical characterization method for molecular interactions and ultrathin films

247th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.