For the past few years, natural products from microbial sources have been used successfully for the development of new biopesticides. Due to their improved efficacy, environmental and non-target safety, and resistance management attributes, these products have been widely promoted as a replacement for synthetic pesticides. Our search for potent and environmentally safe bio-insecticides led to the development of Grandevo� , an advanced bioinsecticide derived from a Chromobacterium subtsugae strain. The ability of Grandevo�  to control a broad spectrum of chewing and sucking insects and mites makes this product ideal for pest management and crop protection. This presentation will discuss bioassay guided isolation and characterization of active compounds, development of analytical markers for QC and mode of action.

Product stewardship: Discovery and development of Grandevo� to commercialization

248th National Meeting (2014)

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