One of the major challenges of efficient crop protection is the recent appearance and proliferation of weed resistance to existing herbicides. The last novel mode of action was discovered and successfully translated into a weed control agent many years ago, meaning there is a pressing need for a novel mode of action to control and eradicate unwanted weeds in agricultural plantations. Indaziflam is the innovative active ingredient of SpecticleTM and AlionTM(first registrations in 2010/2011), which were followed by other brands. This new compound from Bayer CropScience belongs to the alkylazine chemical class and intervenes in cellulose biosynthesis. It is effective against a very wide range of weeds and offers excellent long-term results with very small doses. The discovery process and the optimization of the alkylazine class which led to indaziflam, including biological profiles and the resulting structure-activity-relationships, will be presented.

Indaziflam: An innovative broad spectrum herbicide

248th National Meeting (2014)

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