Newly emerging pests and increasing resistance put a constant pressure on conventional insecticidal classes, thus increasing the need for innovative efficient alternatives with new modes of action. As a result of our continuous efforts to explore novel chemistries and provide sustainable solutions a new class of aminothiazoline insecticides was discovered. Being active against piercing & sucking pests the aminothiazolines act as octopamine receptor agonists in the central nervous system. The compounds show excellent activity against aphids and whiteflies on a broad variety of crops. Having a benzyl amine moiety as a common structural pattern, several different subclasses have been explored under this topic. The potency of the optimized analogs was evaluated under greenhouse and field conditions. Biology, structure-activity relationship of insecticidal aminothiazolines and related subtypes will be presented.

Aminothiazolines: Novel foliar insecticides for the control of piercing-sucking pests

248th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.