Various sized spherical or rod gold and silver nanoparticles are prepared. By modification on surface or coupling with biomolecules, the functionalized nanoparticles are well biocompatible, so they can be used as biomolecular probes to detect amino acids, peptide or protein molecules through molecular interactions. These probes have been applied for detecting occult fingerprints concealed in sweat or blood imprint without damaging the DNA sequences or protein structures in the imprint, which can be further tested for identification information such as DNA sequences. It is also demonstrated that special optical properties of these nanoparticles can be employed in the cancer diagnosis and photothermic therapy.

Study on nanomaterials for detecting biological imprint and potential applications

248th National Meeting (2014)

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