Type 1 diabetes is a pancreatic disease where individuals are not able to produce insulin to control blood glucose levels. A promising approach to control blood sugar for type 1 diabetics is an artificial endocrine pancreas, which continuously reads blood glucose concentrations and automatically controls the insulin/glucagon injections. In this presentation, we will discuss the digital fabrication of a novel flexible amperometric glucose sensor. Additive manufacturing approaches, including electrohydrodynamic (e-jet) printing and electroplating, are being evaluated for rapid optimization of the sensor, improved uniformity, and ultimately reductions in manufacturing costs. The sensor incorporates a plated Ag/AgCl reference electrode and plated platinum indicating electrodes. E-jet printing is used for the deposition and patterning of the glucose oxidase (GOx) enzyme layer and the polymeric permselective membrane, and provides a precise method to control both the thickness and shape of these layers. Details on optimization of the GOx enzyme and polymeric permselective membrane inks and e-jet printed patterns will be discussed, along with electrochemical characterization of the sensors.

Digital fabrication of an amperometric glucose sensor

248th National Meeting (2014)

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