Over the last decade, substantial research has led to the introduction of an impressive number of efficient procedures that allow the selective construction of C-C bonds by directly connecting two different C-H bonds under oxidative conditions. These methodologies have in common that the reactive intermediates are generated in situ by activation of both C-H bonds. This strategy was introduced as the �Cross-Dehydrogenative Coupling� (CDC) and discloses waste-minimized synthetic alternatives to �classic� coupling procedures that rely on the use of prefunctionalized starting materials.  This talk will focus on the use of dioxygen as terminal oxidant for CDC Reactions.Ref. Girard, S. A.; Knauber, T.; Li, C.-J. Angew. Chem. Int. Ed., 2014 , 53, 74-100; Li, C.-J. Acc. Chem. Res. 2009 , 42, 335-344.

Oxidative formation of C-C bonds directly from C-H/C-H bonds with dioxygen as terminal oxidant

248th National Meeting (2014)

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