We established THINQ Pharma to discover and develop new drugs based on the rational principles of reverse pharmacology and systems biology. Scientifically validated and technologically standardized botanical products may be explored on a fast track using innovative approaches based on traditional medicine knowledge. We derive inspiration and intellectual value from ancient wisdom to discover and develop new chemical entities for a variety of pharmaceutical, agrochemical, and cosmoceutical applications. Traditional medicine (complimentary alternative medicine to the western world) has historically involved clinical use of extracts, powders, and other formulations. The extracts have not been standardized, the pure chemical products have rarely been isolated, the biological mechanisms of action have not been elucidated, and the clinical trials have rarely been controlled and documented to international standards. THINQ's goals are to discover and develop these medicines to international standards and introduce them globally after appropriate regulatory filings. THINQ's unique access to discovery and development quantities of isolated natural products with known biological activity through collaboration with practitioners of traditional medicine in India (physicians specializing in AYUSH medicines) combined with our high-speed medicinal chemistry know-how, creates an increased chance of yielding pharmacologically active final products. We present herein selected examples of our research efforts.

Natural products for drug discovery and development: Inspiration from the �ancient" wisdom of Mother Nature

248th National Meeting (2014)

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