Functional polymers with well-defined nanostructures have been explored for various future applications although facile syntheses of these materials are never easy. Recently, our group applies controlled radical polymerizations in a nanometer-sized confine space and produces a core-shell structured hyper-star polymer with uniform size and tunable core composition for labile degradation. The developed facile synthesis allows us to access large-scale (~10 g) uniform hyper-star polymers and explore their properties in siRNA delivery  .

Design a well-defined hyper-star polymer using controlled radical polymerization and explore its application for siRNA delivery

248th National Meeting (2014)

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