Using conventional and microwave-assisted copper�free Sonogashira�type synthesis, we have developed cross�coupling of aryl sulfonates with terminal alkynes.  The steric and electronic effects of the substituents in the aryl sulfonates and terminal alkynes have been investigated.  The corresponding alkyne and enyne products are produced in fair to good yields.  A broad spectrum of arylsulfonates, vinyl sulfonates and terminal alkynes was used. Preliminary results of the synthesis will be presented.

Direct Cu�free Sonogashira cross-coupling reaction of aryl sulfonates with terminal alkynes

248th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.