The PubChem BioAssay database is a public repository of biological test results for drugs, small molecules and RNAi. The database currently contains over 730,000 bioassay protocols, thousands of protein and gene targets, and more than 200 millions of bioactivity outcomes, which were generated by testing 2.9 million chemicals and 180,000 RNAi reagents. Information in PubChem can be freely accessed and downloaded using the NCBI information retrieval system Entrez at http://www.ncbi.nlm.nih.gov/pcassay/ and a suite of services provided by PubChem at http://pubchem.ncbi.nlm.nih.gov. Given the rapidly growing biological data, PubChem is becoming a key information resource for a number of research fields such as chemical biology, medicinal chemistry, drug discovery, and cheminformatics. A bibliometric analysis on applications of the PubChem resource indicates that PubChem is utilized by a broad range of research fields. In particularly, it shows an increasing trend in supporting wet laboratory research towards lead development and drug discovery using the bioassay data. Such an analysis may help to understand the impact of PubChem on biomedical research. It also provides valuable feedback and suggestions for PubChem's future development for better serving the community. PubChem welcomes further contributions from the community by sharing data. Chemical structures and assay results can be deposited via the PubChem submission system at: http://pubchem.ncbi.nlm.nih.gov/upload.

PubChem BioAssay, a public information resource for drug discovery: A bibliometric analysis on PubChem application

248th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.