Design and optimization of heterocyclic 4-azaxanthenes as potent and selective inhibitors of BACE1 for the treatment of Alzheimer's disease

Isaac Marx

Kui Chen

Alan Cheng

Thomas Dineen

Oleg Epstein

Joel Esmay

Dean Hickman

Chuck Kreiman

Robert Wahl

Paul Wen

Matthew Weiss

Douglas Whittington

Stephen Wood

Robert Fremeau

Ryan White

Vinod Patel

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