The importance of amphiphilic block copolymers is undeniable, this being largely associated to their outstanding self-organizing in solution giving rise to different soft materials such as micelles, vesicles, polymersomes and gels. The peculiar behavior of these copolymers in solution allows their use as surfactants, emulsifiers, drug carriers, etc. Some of them reversibly be assembled and disassembled upon ultraviolet exposure.1 The concept needs the incorporation of chromophores into the amphiphilic copolymer structure in terminal position or in pendant chain. The 'decoration' of polyoxazoline (POx)2 as well as the elaboration of POx macromolecular architectures3-5 have extensively been described.In this study we investigated the synthesis of amphiphilic diblock copolymers based on polyoxazoline bearing photo-sensitive group (coumarin). The dimerization of this photochromic moiety was then undertaken after the self-organization into micelle to stabilize the core of the nanoobject. Alternatively, the amphiphilic copolymers have been dimerized into amphiphilic A-B-A triblock copolymers before being self-organized into liposome. According to another route, the photo-cross-linking of amphiphilic grafted copolymers has been studied for the preparation of core-cross-linked micelles. 1: Zhao Y. Macromolecules, 2012 , 45, 2012.2: Guillerm B., Monge S., Lapinte V., Robin J.J. Macromol. Rapid Commun., 2012 , 33, 19, 1600-1612.3: Stemmelen M., Lapinte V., Travelet C., Borsali R., Robin J.J. Polymer Chemistry 2013 , 4, 1445-1458.4: Guillerm B., Darcos V., lapinte V., Monge-Darcos S., Coudane J., Robin J.J. Chem. Commun., 2012 , 48, 2879-2881.5: Guillerm B., Monge S., Lapinte V., Robin J.J. Macromolecules 2010 , 43, 5964-5970.

UV-induced self-assembly of amphiphilic polyoxazolines

248th National Meeting (2014)

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