The need for selective and sensitive analyses of current-use pesticides in crops and food products brought about the development of the QuEChERS method combined with LC-MS/MS analysis.  This presentation will highlight results from ongoing method development projects where a general QUEChERS extraction followed by LC-MS/MS analysis was developed to look at a suite of structurally and functionally variable pesticide residues on a number of crops.  Target pesticides included an organophosphate pesticide (diazinon), a neonicotinoid insecticide (acetamiprid), a carbamate pesticide (carbaryl), a pyrethroid pesticide (permethrin), and amide herbicide (propyzamide) and a triazine herbicide (atrazine).  Crop matrices included brown rice (high carbohydrate), kale (high pigment), egg (high protein), lime (high acid), corn (staple crop), and celery (high moisture).  The matrix of pesticide and crop combinations provides the ability to assess both the extraction and analysis for specificity and sensitivity.  The method meets all QC criteria found in typical regulatory guidelines.  However the results will be discussed in terms of the analytical considerations.  For example the use of solvent calibration solutions versus matrix-matched calibration solutions and the use of an internal standard versus an externally-calibrated method will be discussed.

QuEChERS method for the simultaneous analysis of multiple residues in crops

248th National Meeting (2014)

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