Background  Perfluorinated compounds(PFCs) is an organic fluorine compound that hydrogen of all of the carbon compound was replaced by fluorine. They are a large group of chemicals produced for several decades and widely used for many industrial and consumer applications. Because of their global occurrence in different food and environmental media, their persistence and their potential to bio-accumulate in organisms they are of toxicological and public concern. This study was performed to evaluate PFCs exposure in Korean students and association with their food consumption. Methods  Analysis of internal exposure of 300 middle/high school students to 15 PFCs was performed. Samples were prepared by solid-phase extraction and determined by LC-(ESI)-MS/MS(API 4000, AppliedBioscience) techniques. Method validation was performed with food and serum samples. The limit of detections ranged from 0.05(PFNA) to 0.20(PFBS) ng/mL for human serum samples.  Results  Of the fifteen PFCs, PFOA, PFNA, PFDA, PFHxS, PFOS were detected in most of samples. Mean concentration of PFOA and PFOS were 4.03 and 5.29 ng/mL, respectively. Serum concentration of PFOA and PFOS were positively correlated with age and male sex. The associations with food consumptions varied among PFCs.Conclusions  PFCs concentrations in Korean students were analyzed and 5 PFCs were detected in most of serum samples.

Perfluorinated compounds exposure in Korean students

248th National Meeting (2014)

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