Pyrimidopyridines have been known as fungicides from the 1980s. However, considerable chemical space was available to further explore the potential of this class of compounds against a broad spectrum of diseases. Availability of novel synthesis methodology (e.g.in the transition-metal catalyzed cross couplings area) allowed the preparation of compounds not easily accessible in the 1980's. This poster describes the synthesis, biology, mode of action and resistance risk profile of this chemical class.                                    

Fungicidally active copper chelating agents with low resistance risk

248th National Meeting (2014)

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